TB-500 Thymosin B4 for Sale – TB-500 (Thymosin Beta-4 Acetate) – High Purity ≥99% | cGMP Grade for Tissue Repair & Regenerative Research

TB-500 (Thymosin Beta-4 Acetate) is a synthetic 43-amino acid peptide originally isolated from the thymus gland. It is a naturally occurring regenerative peptide belonging to the β-thymosin family, highly conserved across species and involved in multiple cellular processes including actin binding, tissue repair, and inflammation modulation.

TB-500 is the active fragment of Thymosin Beta-4, responsible for its wound healing and regenerative properties. It functions primarily by binding to G-actin, sequestering it and regulating the actin cytoskeleton. This promotes cell migration, proliferation, and differentiation in damaged tissues.

Research demonstrates TB-500’s ability to promote endothelial cell migration and angiogenesis, reduce inflammation via NF-κB inhibition, and upregulate matrix metalloproteinases (MMPs) for tissue remodeling. It is extensively studied in wound healing, tendon repair, cardiovascular recovery, and neuroprotection models.

At Shanghai AmbioPharm, Inc., we supply high-purity TB-500 (≥99% by HPLC) for advanced regenerative research. Our cGMP-grade material is synthesized in our FDA-inspected Shanghai facility and available for fast U.S. delivery from our Clearwater, South Carolina warehouse.

Key Product Details:

• Sequence: 43-amino acid peptide (active fragment of Thymosin Beta-4)

• Full Name: Thymosin Beta-4 Acetate

• CAS Number: 77591-33-4 (Thymosin Beta-4)

• Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S

• Molecular Weight: 4,963.5 g/mol

• Purity: ≥99% (HPLC)

• Form: Lyophilized white powder

• Storage: -20°C, protected from light, desiccated

• Grade Available: Non-GMP (R&D) and cGMP (clinical preparatory)

• Amino Acids: 43-mer

• Key Property: Actin-binding and sequestering

• Primary Mechanism: G-actin binding, cytoskeletal regulation

TB500 (Thymosin B4 Acetate) for Sale – High Purity Research Peptide

Looking for TB500 (Thymosin B4 Acetate) for sale from a trusted supplier? Shanghai AmbioPharm, Inc. offers high purity TB500 peptide manufactured under advanced, quality-controlled environments to support modern research applications. TB500, also known as Thymosin B4 Acetate, is widely studied in peptide and biochemical research, making it a valuable compound for scientific and laboratory use.

Our TB500 peptide is synthesized using pharmaceutical-grade processes to ensure ≥99% purity, excellent stability, and consistent batch performance. The acetate form enhances peptide stability and handling in research environments. Each order includes a Certificate of Analysis (COA), providing full transparency and verification of product quality. With our manufacturing facility in Shanghai and USA-based distribution support, we ensure fast, secure shipping and dependable supply for both small-scale and bulk orders.

Why Choose AmbioPharm for TB-500?

As a global peptide CDMO, AmbioPharm combines scientific expertise with large-scale manufacturing capabilities. Choosing our TB500 (Thymosin B4 Acetate) for sale ensures premium quality, trusted sourcing, and reliable delivery tailored to your research needs.

• ✅ FDA-inspected cGMP manufacturing

• ✅ Full Certificate of Analysis (COA) with each batch

• ✅ HPLC chromatogram and mass spec data included

• ✅ Verified actin-binding activity confirmation

• ✅ Low endotoxin levels (<1 EU/mg)

• ✅ U.S. warehousing – fast domestic shipping from South Carolina

• ✅ Batch-to-batch consistency for regenerative studies

Research Applications:

• Wound healing and dermal repair research

• Tendon, ligament, and muscle regeneration models

• Angiogenesis and endothelial cell migration studies

• Anti-inflammatory and NF-κB modulation research

• Cardiovascular repair and ischemic injury models

• Neuroprotection and traumatic brain injury research

• Corneal healing and ocular surface repair

• Hair follicle growth and regeneration studies

Mechanism of Action:
TB-500 binds to G-actin, preventing its polymerization into F-actin. This maintains a reservoir of available actin monomers, facilitating rapid cytoskeletal remodeling during cell migration and wound healing. TB-500 also inhibits NF-κB nuclear translocation, reducing pro-inflammatory cytokines (IL-1, IL-6, TNF-α). Additionally, it upregulates matrix metalloproteinases (MMP-1, MMP-2) and promotes endothelial cell migration, angiogenesis, and keratinocyte proliferation.

 Intended Use: For laboratory research purposes only. Not for human consumption or clinical use without regulatory approval.

Ordering Information:

• Minimum Order Quantity (MOQ): 5mg (R&D), 10g+ (cGMP bulk)

• Lead Time: 2-3 weeks (non-GMP), 6-8 weeks (cGMP)

• Shipping: From Clearwater, SC, USA (2-5 days domestic)

• Order today or request a quote to secure high-quality research peptides from a trusted global supplier.