Buy MOTS-c peptide ≥99% purity. cGMP-grade mitochondrial peptide for metabolic, exercise, and longevity research. FDA-inspected CDMO. USA warehouse. Premium MOTS-c Peptide for Sale

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid mitochondrial-derived peptide encoded within the mitochondrial genome. Unlike nuclear-encoded peptides, MOTS-c is transcribed from mitochondrial DNA, representing a novel class of signaling molecules linking mitochondrial function to cellular metabolism.

MOTS-c functions as a hormone-like peptide that regulates metabolic homeostasis. It enhances insulin sensitivity, promotes glucose uptake, reduces adiposity, and increases cellular energy utilization. Research demonstrates its ability to activate AMPK (AMP-activated protein kinase), a master regulator of cellular energy balance, independent of AMP levels.

Looking for Premium MOTS-c Peptide for Sale from a trusted supplier? Shanghai AmbioPharm, Inc. provides high purity MOTS-C peptide manufactured under advanced, quality-controlled environments to support cutting-edge research applications. MOTS-C is a mitochondria-derived peptide widely studied in metabolic and cellular research, making it a valuable compound in modern scientific and biotech laboratories.

Our MOTS-C peptide is synthesized using pharmaceutical-grade processes to ensure ≥99% purity, excellent stability, and consistent batch performance. Each order includes a Certificate of Analysis (COA), ensuring full transparency and verification of product quality. With our manufacturing facility in Shanghai and USA-based distribution support, we ensure fast, secure shipping and dependable supply for both small-scale and bulk orders.

This peptide is particularly significant in aging and metabolic research due to its role in mitochondrial-nuclear communication and metabolic adaptation during exercise.

At Shanghai AmbioPharm, Inc., we supply high-purity MOTS-c (≥99% by HPLC) for advanced metabolic and longevity research. Our cGMP-grade material is synthesized in our FDA-inspected Shanghai facility and available for fast U.S. delivery from our Clearwater, South Carolina warehouse.

Key Product Details:

• Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (16-mer)

• Alternative Sequence Notation: MRWQEMGYIFYPRKLR

• CAS Number: 1627580-64-6

• Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂

• Molecular Weight: 2,174.5 g/mol

• Purity: ≥99% (HPLC)

• Form: Lyophilized white powder

• Storage: -20°C, protected from light, desiccated

• Grade Available: Non-GMP (R&D) and cGMP (clinical preparatory)

• Amino Acids: 16-mer

• Origin: Mitochondrial DNA-encoded (12S rRNA-c)

• Key Mechanism: AMPK activator (AMP-independent)

Why Choose AmbioPharm for MOTS-c?

As a global peptide CDMO, AmbioPharm combines scientific expertise with large-scale manufacturing capabilities. Choosing our Premium MOTS-c Peptide for Sale ensures premium quality, trusted sourcing, and reliable delivery tailored to your research needs.

• ✅ FDA-inspected cGMP manufacturing

• ✅ Full Certificate of Analysis (COA) with each batch

• ✅ HPLC chromatogram and mass spec data included

• ✅ Verified disulfide bond confirmation (if applicable)

• ✅ Low endotoxin levels (<1 EU/mg)

• ✅ U.S. warehousing – fast domestic shipping from South Carolina

• ✅ Batch-to-batch consistency for longitudinal metabolic studies

Research Applications:

• Metabolic homeostasis and insulin sensitivity studies

• Glucose uptake and utilization research

• AMPK activation (AMP-independent pathway)

• Adiposity reduction and weight management models

• Exercise physiology and endurance research

• Mitochondrial-nuclear communication studies

• Aging and longevity research

• Osteoporosis and bone metabolism models

• Circadian rhythm and metabolic adaptation

Mechanism of Action:
MOTS-c enters the nucleus and binds to the transcription factor AHR (Aryl hydrocarbon Receptor), activating AMPK via a non-canonical pathway independent of AMP/ATP ratios. This leads to increased glucose uptake, enhanced fatty acid oxidation, reduced de novo lipogenesis, and improved mitochondrial function. Unlike metformin, MOTS-c activates AMPK directly without metabolic stress.

 Intended Use: For laboratory research purposes only. Not for human consumption or clinical use without regulatory approval.

Ordering Information:

• Minimum Order Quantity (MOQ): 5mg (R&D), 10g+ (cGMP bulk)

• Lead Time: 2-3 weeks (non-GMP), 6-8 weeks (cGMP)

• Shipping: From Clearwater, SC, USA (2-5 days domestic)